24. Synthesis of a Cyclopropane Derivative
Cyclopropanation is a typical reaction of alkenes. But how are we going to assemble the rest of the molecule?
The key to this synthesis is to recognize that we’re making a cis-substituted cyclopropane, which means that the predecessor must be a cis-alkene. How do we make a cis-alkene? The most straightforward way is via the Witting reaction.
Reactions that we are going to see in this synthesis include:
