05. Synthesis of Dioxane from Acetylene

The key aspect of this synthesis is to recognize that while our final product (target molecule) might looks like a complex cyclic structure, it’s nothing more than just a simple ether. And how to we make ethers? Right, via the Williamson ether synthesis. So, this entire synthesis boils down to a simple transformation of our acetylene starting material into two reagents for the Williamson: a dihalide and a diol.

Post a comment

Leave a Comment

Your email address will not be published. Required fields are marked *