Reactions of Alcohols

Alcohol function is an extremely versatile functional group in organic chemistry. Reactions of alcohols involve oxidations, substitutions, and eliminations giving you a significant advantage in synthesis and functional group modifications. Reactions of alcohols is a typical topic in a sophomore organic chemistry and is covered in either first or second semester depending on the instructor’s …

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Pinacol Rearrangement

Pinacol rearrangement is a specific elimination reaction that vicinal diols go through in acidic conditions. Unlike a typical E1 reaction that gives you an alkene, the pinacol rearrangement gives you an aldehyde or a ketone instead. Here’s the general scheme for the reaction: As you can see, the pinacol rearrangement also causes the carbon backbone …

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